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Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations
The human APOBEC3G (A3G) protein is a cellular polynucleotide cytidine deaminase that acts as a host restriction factor of retroviruses, including HIV-1 and various transposable elements. Recently, three NMR and two crystal structures of the catalytic deaminase domain of A3G have been reported, but...
Autores principales: | Autore, Flavia, Bergeron, Julien R. C., Malim, Michael H., Fraternali, Franca, Huthoff, Hendrik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902501/ https://www.ncbi.nlm.nih.gov/pubmed/20635000 http://dx.doi.org/10.1371/journal.pone.0011515 |
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