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The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation

BACKGROUND: Clock genes and their protein products regulate circadian rhythms in mammals but have also been implicated in various physiological processes, including bone formation. Osteoblasts build new mineralized bone whereas osteoclasts degrade it thereby balancing bone formation. To evaluate the...

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Detalles Bibliográficos
Autores principales: Maronde, Erik, Schilling, Arndt F., Seitz, Sebastian, Schinke, Thorsten, Schmutz, Isabelle, van der Horst, Gijsbertus, Amling, Michael, Albrecht, Urs
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902506/
https://www.ncbi.nlm.nih.gov/pubmed/20634945
http://dx.doi.org/10.1371/journal.pone.0011527