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Does mild COPD affect prognosis in the elderly?

BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects independence and survival in the general population, but it is unknown to which extent this conclusion applies to elderly people with mild disease. The aim of this study was to verify whether mild COPD, defined according to different c...

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Autores principales: Pedone, Claudio, Scarlata, Simone, Sorino, Claudio, Forastiere, Francesco, Bellia, Vincenzo, Antonelli Incalzi, Raffaele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903556/
https://www.ncbi.nlm.nih.gov/pubmed/20529281
http://dx.doi.org/10.1186/1471-2466-10-35
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author Pedone, Claudio
Scarlata, Simone
Sorino, Claudio
Forastiere, Francesco
Bellia, Vincenzo
Antonelli Incalzi, Raffaele
author_facet Pedone, Claudio
Scarlata, Simone
Sorino, Claudio
Forastiere, Francesco
Bellia, Vincenzo
Antonelli Incalzi, Raffaele
author_sort Pedone, Claudio
collection PubMed
description BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects independence and survival in the general population, but it is unknown to which extent this conclusion applies to elderly people with mild disease. The aim of this study was to verify whether mild COPD, defined according to different classification systems (ATS/ERS, BTS, GOLD) impacts independence and survival in elderly (aged 65 to 74 years) or very elderly (aged 75 years or older) patients. METHODS: We used data coming from the Respiratory Health in the Elderly (Salute Respiratoria nell'Anziano, SaRA) study and compared the differences between the classification systems with regards to personal capabilities and 5-years survival, focusing on the mild stage of COPD. RESULTS: We analyzed data from 1,159 patients (49% women) with a mean age of 73.2 years (SD: 6.1). One third of participants were 75 years or older. Mild COPD, whichever was its definition, was not associated with worse personal capabilities or increased mortality after adjustment for potential confounders in both age groups. CONCLUSIONS: Mild COPD may not affect survival or personal independence of patients over 65 years of age if the reference group consists of patients with a comparable burden of non respiratory diseases. Comorbidity and age itself likely are main determinants of both outcomes.
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spelling pubmed-29035562010-07-14 Does mild COPD affect prognosis in the elderly? Pedone, Claudio Scarlata, Simone Sorino, Claudio Forastiere, Francesco Bellia, Vincenzo Antonelli Incalzi, Raffaele BMC Pulm Med Research article BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects independence and survival in the general population, but it is unknown to which extent this conclusion applies to elderly people with mild disease. The aim of this study was to verify whether mild COPD, defined according to different classification systems (ATS/ERS, BTS, GOLD) impacts independence and survival in elderly (aged 65 to 74 years) or very elderly (aged 75 years or older) patients. METHODS: We used data coming from the Respiratory Health in the Elderly (Salute Respiratoria nell'Anziano, SaRA) study and compared the differences between the classification systems with regards to personal capabilities and 5-years survival, focusing on the mild stage of COPD. RESULTS: We analyzed data from 1,159 patients (49% women) with a mean age of 73.2 years (SD: 6.1). One third of participants were 75 years or older. Mild COPD, whichever was its definition, was not associated with worse personal capabilities or increased mortality after adjustment for potential confounders in both age groups. CONCLUSIONS: Mild COPD may not affect survival or personal independence of patients over 65 years of age if the reference group consists of patients with a comparable burden of non respiratory diseases. Comorbidity and age itself likely are main determinants of both outcomes. BioMed Central 2010-06-07 /pmc/articles/PMC2903556/ /pubmed/20529281 http://dx.doi.org/10.1186/1471-2466-10-35 Text en Copyright ©2010 Pedone et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research article
Pedone, Claudio
Scarlata, Simone
Sorino, Claudio
Forastiere, Francesco
Bellia, Vincenzo
Antonelli Incalzi, Raffaele
Does mild COPD affect prognosis in the elderly?
title Does mild COPD affect prognosis in the elderly?
title_full Does mild COPD affect prognosis in the elderly?
title_fullStr Does mild COPD affect prognosis in the elderly?
title_full_unstemmed Does mild COPD affect prognosis in the elderly?
title_short Does mild COPD affect prognosis in the elderly?
title_sort does mild copd affect prognosis in the elderly?
topic Research article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903556/
https://www.ncbi.nlm.nih.gov/pubmed/20529281
http://dx.doi.org/10.1186/1471-2466-10-35
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