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Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production
BACKGROUND: Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. A second member of this family, Themis2 (Q91YX0), also known as ICB1 (Induced on contact with basement membrane 1)...
Autores principales: | Peirce, Matthew J., Brook, Matthew, Morrice, Nicholas, Snelgrove, Robert, Begum, Shajna, Lanfrancotti, Alessandra, Notley, Clare, Hussell, Tracy, Cope, Andrew P., Wait, Robin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903609/ https://www.ncbi.nlm.nih.gov/pubmed/20644716 http://dx.doi.org/10.1371/journal.pone.0011465 |
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