Cargando…

An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors

PURPOSE: Prostate stem cell antigen (PSCA), a cell surface glycoprotein expressed in normal human prostate and bladder, is over-expressed in the majority of localized prostate cancer and most bone metastases. We have previously shown that the hu1G8 minibody, a humanized anti-PSCA antibody fragment (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lepin, Eric J., Leyton, Jeffrey V., Zhou, Yu, Olafsen, Tove, Salazar, Felix B., McCabe, Katelyn E., Hahm, Scott, Marks, James D., Reiter, Robert E., Wu, Anna M.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903645/ https://www.ncbi.nlm.nih.gov/pubmed/20354850 http://dx.doi.org/10.1007/s00259-010-1433-1

Ejemplares similares

Dual-Modality ImmunoPET/Fluorescence Imaging of Prostate Cancer with an Anti-PSCA Cys-Minibody
por: Tsai, Wenting K, et al.
Publicado: (2018)

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors
por: Bäck, Tom A., et al.
Publicado: (2020)

Pet imaging of cytotoxic human T cells using an 89Zr-labeled anti-CD8 minibody
por: Olafsen, Tove, et al.
Publicado: (2015)

CA19-9 as a Potential Target for Radiolabeled Antibody-Based Positron Emission Tomography of Pancreas Cancer
por: Girgis, Mark D., et al.
Publicado: (2011)

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment
por: Girgis, Mark D, et al.
Publicado: (2011)

PSCA is a target of chimeric antigen receptor T cells in gastric cancer
por: Wu, Di, et al.
Publicado: (2020)

Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer
por: Priceman, Saul J., et al.
Publicado: (2017)

First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody
por: Omidvari, Negar, et al.
Publicado: (2023)

First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody
por: Omidvari, Negar, et al.
Publicado: (2023)

Impact of PSCA Variation on Gastric Ulcer Susceptibility
por: Tanikawa, Chizu, et al.
Publicado: (2013)

Impact of PSCA Polymorphisms on the Risk of Duodenal Ulcer
por: Usui, Yoshiaki, et al.
Publicado: (2021)

Prostate stem cell antigen (PSCA) and risk of bladder cancer: linking genotypes to functional mechanisms
por: Mumy, Adam, et al.
Publicado: (2011)

Evaluation of Two Internalizing Carcinoembryonic Antigen Reporter Genes for Molecular Imaging
por: Barat, Bhaswati, et al.
Publicado: (2010)

On the Rapid Calculation of Binding Affinities for Antigen and Antibody Design and Affinity Maturation Simulations
por: Conti, Simone, et al.
Publicado: (2022)

Human Anti-CCR4 Minibody Gene Transfer for the Treatment of Cutaneous T-Cell Lymphoma
por: Han, Thomas, et al.
Publicado: (2012)

Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR Receptor
por: Kim, Young Pil, et al.
Publicado: (2014)

PSCA rs2294008 Polymorphism with Increased Risk of Cancer
por: Geng, Peiliang, et al.
Publicado: (2015)

Correction: Impact of PSCA Variation on Gastric Ulcer Susceptibility
Publicado: (2014)

Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life
por: Andersen, Jan Terje, et al.
Publicado: (2012)

Correction: Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR Receptor
Publicado: (2015)

PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population
por: Qiu, Li-Xin, et al.
Publicado: (2016)

The Correlation between PSCA Expression and Neuroendocrine Differentiation in Prostate Cancer
por: Xiang, Qian, et al.
Publicado: (2020)

Exploring the Tumor-Suppressing Potential of PSCA in Pancreatic Ductal Adenocarcinoma
por: Li, Kexin, et al.
Publicado: (2023)

Downregulation of PSCA promotes gastric cancer proliferation and is related to poor prognosis
por: Xu, Li-pu, et al.
Publicado: (2020)

Preclinical Characterization of the (177)Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5
por: Striese, Franziska, et al.
Publicado: (2023)

Fibroblast Activation Protein-Targeting Minibody-IRDye700DX for Ablation of the Cancer-Associated Fibroblast with Photodynamic Therapy
por: Smeets, Esther M. M., et al.
Publicado: (2023)

Development and optimization of PSCA-specific CAR T cells for the treatment of bone metastatic prostate cancer
por: Gerdts, Ethan, et al.
Publicado: (2015)

Genetic variation in PSCA gene and bladder cancer susceptibility in North Indian population
por: Jaiswal, Praveen K, et al.
Publicado: (2014)

PSCA rs2294008 C > T polymorphism contributes to gastric and bladder cancer risk
por: Wang, Meng, et al.
Publicado: (2015)

Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population
por: Wang, Meng, et al.
Publicado: (2016)

Impact of PSCA gene polymorphisms in modulating gastric cancer risk in the Chinese population
por: Yan, Kangpeng, et al.
Publicado: (2019)

Genetic variation of the PSCA gene (rs2294008) is not associated with the risk of prostate cancer
por: Lee, Il-Seok, et al.
Publicado: (2017)

Optimizing the Preparation Procedure of Recombinant PSCA, as a Practical Biomarker in Prostate Cancer
por: Shahrabi Farahani, Mahboube, et al.
Publicado: (2021)

Antigen specificity and tumour targeting efficiency of a human carcinoembryonic antigen-specific scFv and affinity-matured derivatives.
por: Jackson, H., et al.
Publicado: (1998)

Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
por: Sioud, Mouldy, et al.
Publicado: (2021)

Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer
por: Zhigang, Zhao, et al.
Publicado: (2004)

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”
por: Feldmann, Anja, et al.
Publicado: (2017)

Dendritic Cell-Directed Vaccination with a Lentivector Encoding PSCA for Prostate Cancer in Mice
por: Xiao, Liang, et al.
Publicado: (2012)

Diagnostic Efficacy of PSMA and PSCA mRNAs Combined to PSA in Prostate Cancer Patients
por: Mahmoud, Mustafa M, et al.
Publicado: (2023)

Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory
por: Chaplin, Jay W., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qkf8bciejdkjqrrkgt3gmkaeo5