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An evolutionary approach to Function
BACKGROUND: Understanding the distinction between function and role is vexing and difficult. While it appears to be useful, in practice this distinction is hard to apply, particularly within biology. RESULTS: I take an evolutionary approach, considering a series of examples, to develop and generate...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903723/ https://www.ncbi.nlm.nih.gov/pubmed/20626924 http://dx.doi.org/10.1186/2041-1480-1-S1-S4 |
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author | Lord, Phillip |
author_facet | Lord, Phillip |
author_sort | Lord, Phillip |
collection | PubMed |
description | BACKGROUND: Understanding the distinction between function and role is vexing and difficult. While it appears to be useful, in practice this distinction is hard to apply, particularly within biology. RESULTS: I take an evolutionary approach, considering a series of examples, to develop and generate definitions for these concepts. I test them in practice against the Ontology for Biomedical Investigations (OBI). Finally, I give an axiomatisation and discuss methods for applying these definitions in practice. CONCLUSIONS: The definitions in this paper are applicable, formalizing current practice. As such, they make a significant contribution to the use of these concepts within biomedical ontologies. |
format | Text |
id | pubmed-2903723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-29037232010-07-14 An evolutionary approach to Function Lord, Phillip J Biomed Semantics Proceedings BACKGROUND: Understanding the distinction between function and role is vexing and difficult. While it appears to be useful, in practice this distinction is hard to apply, particularly within biology. RESULTS: I take an evolutionary approach, considering a series of examples, to develop and generate definitions for these concepts. I test them in practice against the Ontology for Biomedical Investigations (OBI). Finally, I give an axiomatisation and discuss methods for applying these definitions in practice. CONCLUSIONS: The definitions in this paper are applicable, formalizing current practice. As such, they make a significant contribution to the use of these concepts within biomedical ontologies. BioMed Central 2010-06-22 /pmc/articles/PMC2903723/ /pubmed/20626924 http://dx.doi.org/10.1186/2041-1480-1-S1-S4 Text en Copyright ©2010 Lord; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Proceedings Lord, Phillip An evolutionary approach to Function |
title | An evolutionary approach to Function |
title_full | An evolutionary approach to Function |
title_fullStr | An evolutionary approach to Function |
title_full_unstemmed | An evolutionary approach to Function |
title_short | An evolutionary approach to Function |
title_sort | evolutionary approach to function |
topic | Proceedings |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903723/ https://www.ncbi.nlm.nih.gov/pubmed/20626924 http://dx.doi.org/10.1186/2041-1480-1-S1-S4 |
work_keys_str_mv | AT lordphillip anevolutionaryapproachtofunction AT lordphillip evolutionaryapproachtofunction |