Cannabinoids and Viral Infections

Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antivi...

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Detalles Bibliográficos
Autor principal: Reiss, Carol Shoshkes
Formato: Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903762/
https://www.ncbi.nlm.nih.gov/pubmed/20634917
http://dx.doi.org/10.3390/ph3061873
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author Reiss, Carol Shoshkes
author_facet Reiss, Carol Shoshkes
author_sort Reiss, Carol Shoshkes
collection PubMed
description Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca(2+) activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections.
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spelling pubmed-29037622010-07-14 Cannabinoids and Viral Infections Reiss, Carol Shoshkes Pharmaceuticals (Basel) Review Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca(2+) activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections. MDPI 2010-06-09 /pmc/articles/PMC2903762/ /pubmed/20634917 http://dx.doi.org/10.3390/ph3061873 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Reiss, Carol Shoshkes
Cannabinoids and Viral Infections
title Cannabinoids and Viral Infections
title_full Cannabinoids and Viral Infections
title_fullStr Cannabinoids and Viral Infections
title_full_unstemmed Cannabinoids and Viral Infections
title_short Cannabinoids and Viral Infections
title_sort cannabinoids and viral infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903762/
https://www.ncbi.nlm.nih.gov/pubmed/20634917
http://dx.doi.org/10.3390/ph3061873
work_keys_str_mv AT reisscarolshoshkes cannabinoidsandviralinfections

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