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DELAYED TREATMENT EFFECTS OF XANTHINE OXIDASE INHIBITION ON SYSTOLIC OVERLOAD-INDUCED LEFT VENTRICULAR HYPERTROPHY AND DYSFUNCTION
The nonpurine selective xanthine oxidase (XO) inhibitor febuxostat attenuates development of left ventricular (LV) hypertrophy and dysfunction in mice when treatment is initiated within 1 hour of transverse aortic constriction (TAC). This study investigated whether a 7-day delay of treatment with th...
Autores principales: | Xu, X., Zhao, L., Hu, X., Zhang, P., Wessale, J., Bache, R., Chen, Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903770/ https://www.ncbi.nlm.nih.gov/pubmed/20544512 http://dx.doi.org/10.1080/15257771003738683 |
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