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Dysregulation of l-arginine metabolism and bioavailability associated to free plasma heme

Severe Plasmodium falciparum malaria is associated with hypoargininemia, which contributes to impaired systemic and pulmonary nitric oxide (NO) production and endothelial dysfunction. Since intravascular hemolysis is an intrinsic feature of severe malaria, we investigated whether and by which mechan...

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Detalles Bibliográficos
Autores principales: Omodeo-Salè, F., Cortelezzi, L., Vommaro, Z., Scaccabarozzi, D., Dondorp, A. M.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904256/
https://www.ncbi.nlm.nih.gov/pubmed/20357184
http://dx.doi.org/10.1152/ajpcell.00405.2009