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Dysregulation of l-arginine metabolism and bioavailability associated to free plasma heme
Severe Plasmodium falciparum malaria is associated with hypoargininemia, which contributes to impaired systemic and pulmonary nitric oxide (NO) production and endothelial dysfunction. Since intravascular hemolysis is an intrinsic feature of severe malaria, we investigated whether and by which mechan...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904256/ https://www.ncbi.nlm.nih.gov/pubmed/20357184 http://dx.doi.org/10.1152/ajpcell.00405.2009 |