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Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2

BACKGROUND: Using a murine model of herpes simplex virus (HSV)-1 encephalitis, our laboratory has determined that induction of proinflammatory mediators in response to viral infection is largely mediated through a Toll-like receptor-2 (TLR2)-dependent mechanism. Published studies have shown that, li...

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Detalles Bibliográficos
Autores principales: Schachtele, Scott J, Hu, Shuxian, Little, Morgan R, Lokensgard, James R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904293/
https://www.ncbi.nlm.nih.gov/pubmed/20584314
http://dx.doi.org/10.1186/1742-2094-7-35