Cargando…
Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2
BACKGROUND: Using a murine model of herpes simplex virus (HSV)-1 encephalitis, our laboratory has determined that induction of proinflammatory mediators in response to viral infection is largely mediated through a Toll-like receptor-2 (TLR2)-dependent mechanism. Published studies have shown that, li...
Autores principales: | Schachtele, Scott J, Hu, Shuxian, Little, Morgan R, Lokensgard, James R |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904293/ https://www.ncbi.nlm.nih.gov/pubmed/20584314 http://dx.doi.org/10.1186/1742-2094-7-35 |
Ejemplares similares
-
Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia
por: Aravalli, Rajagopal N, et al.
Publicado: (2007) -
Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia
por: Hu, Shuxian, et al.
Publicado: (2011) -
Modulation of Experimental Herpes Encephalitis-Associated Neurotoxicity through Sulforaphane Treatment
por: Schachtele, Scott J., et al.
Publicado: (2012) -
Toll like receptors: Sensors for herpes simplex virus infection
por: Govindan, Balaji
Publicado: (2014) -
Toll-like receptor 3 deficiency in autoimmune encephalitis post–herpes simplex encephalitis
por: Armangue, Thaís, et al.
Publicado: (2019)