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MPRAP: An accessibility predictor for a-helical transmem-brane proteins that performs well inside and outside the membrane

BACKGROUND: In water-soluble proteins it is energetically favorable to bury hydrophobic residues and to expose polar and charged residues. In contrast to water soluble proteins, transmembrane proteins face three distinct environments; a hydrophobic lipid environment inside the membrane, a hydrophili...

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Detalles Bibliográficos
Autores principales: Illergård, Kristoffer, Callegari, Simone, Elofsson, Arne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904353/
https://www.ncbi.nlm.nih.gov/pubmed/20565847
http://dx.doi.org/10.1186/1471-2105-11-333