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Pulmonary Kaposi's sarcoma after heart transplantation: a case report

INTRODUCTION: Kaposi's sarcomas have been associated with different conditions of immunosuppression and are also known to be a typical complication of solid organ transplantations. CASE PRESENTATION: We report the case of a 65-year-old Turkish man with a history of heart transplantation 10 mont...

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Detalles Bibliográficos
Autores principales: Fritzsche, Florian R, Tutic, Michaela, Opitz, Isabelle, Hunziker, Roger, Kristiansen, Glen, Montani, Matteo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904355/
https://www.ncbi.nlm.nih.gov/pubmed/20602747
http://dx.doi.org/10.1186/1752-1947-4-206
Descripción
Sumario:INTRODUCTION: Kaposi's sarcomas have been associated with different conditions of immunosuppression and are also known to be a typical complication of solid organ transplantations. CASE PRESENTATION: We report the case of a 65-year-old Turkish man with a history of heart transplantation 10 months ago who presented for clarification of his dyspnea. The patient had a known history of chronic obstructive pulmonary disease and a smoking history of 40 pack years. Radiologically, three progressively growing intra-pulmonary nodules were detected. The histology was diagnostic for a Kaposi's sarcoma. Visceral and especially primary intra-pulmonary Kaposi's sarcomas are very rare and have been described to have a rather unfavorable prognosis. CONCLUSIONS: Even with a history suggestive for conventional lung cancer, Kaposi's sarcomas should be considered in patients after transplantation of solid organs. It should be noted that in a minority of cases this tumor exists in the absence of the typical cutaneous lesions.