Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients

Mutations in CuZn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) and are found in 6% of ALS patients. Non-native and aggregation-prone forms of mutant SOD1s are thought to trigger the disease. Two sets of novel antibodies, raised in rabbits and chicken, against peptides spaced...

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Detalles Bibliográficos
Autores principales: Forsberg, Karin, Jonsson, P. Andreas, Andersen, Peter M., Bergemalm, Daniel, Graffmo, Karin S., Hultdin, Magnus, Jacobsson, Johan, Rosquist, Roland, Marklund, Stefan L., Brännström, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904380/
https://www.ncbi.nlm.nih.gov/pubmed/20644736
http://dx.doi.org/10.1371/journal.pone.0011552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904380/
https://www.ncbi.nlm.nih.gov/pubmed/20644736
http://dx.doi.org/10.1371/journal.pone.0011552

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