Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System

The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn(2+), Cu(2+), Mg(2+), Se(2+)), in “green media” and evaluate its stability in vitro compared to curcumin alone. The curcumin complexes were prepared by mechanical mixture of curcumin an...

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Detalles Bibliográficos
Autores principales: Zebib, Bachar, Mouloungui, Zéphirin, Noirot, Virginie
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904446/
https://www.ncbi.nlm.nih.gov/pubmed/20634909
http://dx.doi.org/10.1155/2010/292760
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author Zebib, Bachar
Mouloungui, Zéphirin
Noirot, Virginie
author_facet Zebib, Bachar
Mouloungui, Zéphirin
Noirot, Virginie
author_sort Zebib, Bachar
collection PubMed
description The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn(2+), Cu(2+), Mg(2+), Se(2+)), in “green media” and evaluate its stability in vitro compared to curcumin alone. The curcumin complexes were prepared by mechanical mixture of curcumin and sulfate salts of each metal (metal : curcumin 1/1mol) into unconventional and nontoxic glycerol/water solvent. Two stoichiometry of complex were obtained, 1 : 1 and 1 : 2 (metal/curcumin), respectively. On evaluation of in vitro stability, all complexes were found to provide a higher stability from curcumin alone.
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spelling pubmed-29044462010-07-15 Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System Zebib, Bachar Mouloungui, Zéphirin Noirot, Virginie Bioinorg Chem Appl Research Article The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn(2+), Cu(2+), Mg(2+), Se(2+)), in “green media” and evaluate its stability in vitro compared to curcumin alone. The curcumin complexes were prepared by mechanical mixture of curcumin and sulfate salts of each metal (metal : curcumin 1/1mol) into unconventional and nontoxic glycerol/water solvent. Two stoichiometry of complex were obtained, 1 : 1 and 1 : 2 (metal/curcumin), respectively. On evaluation of in vitro stability, all complexes were found to provide a higher stability from curcumin alone. Hindawi Publishing Corporation 2010 2010-06-16 /pmc/articles/PMC2904446/ /pubmed/20634909 http://dx.doi.org/10.1155/2010/292760 Text en Copyright © 2010 Bachar Zebib et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zebib, Bachar
Mouloungui, Zéphirin
Noirot, Virginie
Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title_full Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title_fullStr Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title_full_unstemmed Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title_short Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
title_sort stabilization of curcumin by complexation with divalent cations in glycerol/water system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904446/
https://www.ncbi.nlm.nih.gov/pubmed/20634909
http://dx.doi.org/10.1155/2010/292760
work_keys_str_mv AT zebibbachar stabilizationofcurcuminbycomplexationwithdivalentcationsinglycerolwatersystem
AT moulounguizephirin stabilizationofcurcuminbycomplexationwithdivalentcationsinglycerolwatersystem
AT noirotvirginie stabilizationofcurcuminbycomplexationwithdivalentcationsinglycerolwatersystem

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