Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats

The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor γ (TRG) as well as the corresponding RSSs retrieved from Trace Archive...

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Detalles Bibliográficos
Autores principales: Weiss, Alexander Thomas Andreas, Hecht, Werner, Reinacher, Manfred
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904447/
https://www.ncbi.nlm.nih.gov/pubmed/20634910
http://dx.doi.org/10.4061/2010/953272
Descripción
Sumario:The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor γ (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor γ locus are also described.

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