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Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor γ (TRG) as well as the corresponding RSSs retrieved from Trace Archive...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904447/ https://www.ncbi.nlm.nih.gov/pubmed/20634910 http://dx.doi.org/10.4061/2010/953272 |
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author | Weiss, Alexander Thomas Andreas Hecht, Werner Reinacher, Manfred |
author_facet | Weiss, Alexander Thomas Andreas Hecht, Werner Reinacher, Manfred |
author_sort | Weiss, Alexander Thomas Andreas |
collection | PubMed |
description | The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor γ (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor γ locus are also described. |
format | Text |
id | pubmed-2904447 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-29044472010-07-15 Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats Weiss, Alexander Thomas Andreas Hecht, Werner Reinacher, Manfred Vet Med Int Research Article The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor γ (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor γ locus are also described. SAGE-Hindawi Access to Research 2010-06-16 /pmc/articles/PMC2904447/ /pubmed/20634910 http://dx.doi.org/10.4061/2010/953272 Text en Copyright © 2010 Alexander Thomas Andreas Weiss et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Weiss, Alexander Thomas Andreas Hecht, Werner Reinacher, Manfred Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title | Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_full | Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_fullStr | Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_full_unstemmed | Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_short | Feline T-Cell Receptor γ V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_sort | feline t-cell receptor γ v- and j-region sequences retrieved from the trace archive and from transcriptome analysis of cats |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904447/ https://www.ncbi.nlm.nih.gov/pubmed/20634910 http://dx.doi.org/10.4061/2010/953272 |
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