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Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets

BACKGROUND: RNA-mediated interference (RNAi)-based functional genomics is a systems-level approach to identify novel genes that control biological phenotypes. Existing computational approaches can identify individual genes from RNAi datasets that regulate a given biological process. However, current...

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Detalles Bibliográficos
Autores principales: Ho, Hsiang, Milenković, Tijana, Memišević, Vesna, Aruri, Jayavani, Pržulj, Nataša, Ganesan, Anand K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904735/
https://www.ncbi.nlm.nih.gov/pubmed/20550706
http://dx.doi.org/10.1186/1752-0509-4-84