Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

BACKGROUND: Cellular senescence is a permanent growth arrest that occurs in response to cellular stressors, such as telomere shortening or activation of oncogenes. Although the process of senescence growth arrest is somewhat conserved between mouse and human cells, there are some critical difference...

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Detalles Bibliográficos
Autores principales: Kennedy, Alyssa L, McBryan, Tony, Enders, Greg H, Johnson, F Brad, Zhang, Rugang, Adams, Peter D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904742/
https://www.ncbi.nlm.nih.gov/pubmed/20569479
http://dx.doi.org/10.1186/1747-1028-5-16

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