Down-Regulation of Telomerase Activity and Activation of Caspase-3 Are Responsible for Tanshinone I-Induced Apoptosis in Monocyte Leukemia Cells in Vitro

Tanshinone I (Tan-I) is a diterpene quinone extracted from the traditional herbal medicine Salvia miltiorrhiza Bunge. Recently, Tan-I has been reported to have anti-tumor effects. In this study, we investigated the growth inhibition and apoptosis inducing effects of Tan-I on three kinds of monocytic...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Dan, Fan, Rui-Fang, Zhang, Yong, Yang, Hong-Zhi, Fang, Zhi-Gang, Guan, Wei-Bing, Lin, Dong-Jun, Xiao, Ruo-Zhi, Huang, Ren-Wei, Huang, He-Qing, Liu, Pei-Qing, Liu, Jia-Jun
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904915/
https://www.ncbi.nlm.nih.gov/pubmed/20640151
http://dx.doi.org/10.3390/ijms11062267

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