ABO blood group and other genetic variants associated with pancreatic cancer

Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. Recent reports, including genome-wide association studies and self-reported blood serotype studies, have shown that individuals of European ancestry who carry non-O blood group are at an increased risk of dev...

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Autores principales: Lennon, Anne Marie, Klein, Alison P, Goggins, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905099/
https://www.ncbi.nlm.nih.gov/pubmed/20587082
http://dx.doi.org/10.1186/gm160
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author Lennon, Anne Marie
Klein, Alison P
Goggins, Michael
author_facet Lennon, Anne Marie
Klein, Alison P
Goggins, Michael
author_sort Lennon, Anne Marie
collection PubMed
description Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. Recent reports, including genome-wide association studies and self-reported blood serotype studies, have shown that individuals of European ancestry who carry non-O blood group are at an increased risk of developing pancreatic cancer. Two recent genome-wide association studies of pancreatic cancer have identified associations between pancreatic cancer risk and genetic variants in the ABO blood group gene, the locus containing the telomerase reverse transcriptase (hTERT) gene, the nuclear receptor family gene NR5A2 and a non-genic region on chromosome 13q22.1.
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spelling pubmed-29050992011-06-22 ABO blood group and other genetic variants associated with pancreatic cancer Lennon, Anne Marie Klein, Alison P Goggins, Michael Genome Med Minireview Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. Recent reports, including genome-wide association studies and self-reported blood serotype studies, have shown that individuals of European ancestry who carry non-O blood group are at an increased risk of developing pancreatic cancer. Two recent genome-wide association studies of pancreatic cancer have identified associations between pancreatic cancer risk and genetic variants in the ABO blood group gene, the locus containing the telomerase reverse transcriptase (hTERT) gene, the nuclear receptor family gene NR5A2 and a non-genic region on chromosome 13q22.1. BioMed Central 2010-06-22 /pmc/articles/PMC2905099/ /pubmed/20587082 http://dx.doi.org/10.1186/gm160 Text en Copyright ©2010 BioMed Central Ltd.
spellingShingle Minireview
Lennon, Anne Marie
Klein, Alison P
Goggins, Michael
ABO blood group and other genetic variants associated with pancreatic cancer
title ABO blood group and other genetic variants associated with pancreatic cancer
title_full ABO blood group and other genetic variants associated with pancreatic cancer
title_fullStr ABO blood group and other genetic variants associated with pancreatic cancer
title_full_unstemmed ABO blood group and other genetic variants associated with pancreatic cancer
title_short ABO blood group and other genetic variants associated with pancreatic cancer
title_sort abo blood group and other genetic variants associated with pancreatic cancer
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905099/
https://www.ncbi.nlm.nih.gov/pubmed/20587082
http://dx.doi.org/10.1186/gm160
work_keys_str_mv AT lennonannemarie abobloodgroupandothergeneticvariantsassociatedwithpancreaticcancer
AT kleinalisonp abobloodgroupandothergeneticvariantsassociatedwithpancreaticcancer
AT gogginsmichael abobloodgroupandothergeneticvariantsassociatedwithpancreaticcancer

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