Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease

Vaccine-based autoimmune (anti-amyloid) treatments are currently being examined for their therapeutic potential in Alzheimer's disease. In the present study we examined, in a transgenic model of amyloid pathology, the expression of two molecules previously implicated in decreasing the severity...

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Detalles Bibliográficos
Autores principales: Melchior, Benoit, Garcia, Angie E, Hsiung, Bor-Kai, Lo, Katherine M, Doose, Jonathan M, Cameron Thrash, J, Stalder, Anna K, Staufenbiel, Matthias, Neumann, Harald, Carson, Monica J
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905103/
https://www.ncbi.nlm.nih.gov/pubmed/20640189
http://dx.doi.org/10.1042/AN20100010

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