Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses

Splicing is regulated by complex interactions of numerous RNA-binding proteins. The molecular mechanisms involved remain elusive, in large part because of ignorance regarding the numbers of proteins in regulatory complexes. Polypyrimidine tract-binding protein (PTB), which regulates tissue-specific...

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Detalles Bibliográficos
Autores principales: Cherny, Dmitry, Gooding, Clare, Eperon, Giles E, Coelho, Miguel B, Bagshaw, Clive R, Smith, Christopher W J, Eperon, Ian C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905242/
https://www.ncbi.nlm.nih.gov/pubmed/20502437
http://dx.doi.org/10.1038/emboj.2010.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905242/
https://www.ncbi.nlm.nih.gov/pubmed/20502437
http://dx.doi.org/10.1038/emboj.2010.103

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