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PHD2 in tumour angiogenesis
Originally identified as the enzymes responsible for catalysing the oxidation of specific, conserved proline residues within hypoxia-inducible factor-1α (HIF-1α), the additional roles for the prolyl hydroxylase domain (PHD) proteins have remained elusive. Of the four identified PHD enzymes, PHD2 is...
Autores principales: | Chan, D A, Giaccia, A J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905285/ https://www.ncbi.nlm.nih.gov/pubmed/20461086 http://dx.doi.org/10.1038/sj.bjc.6605682 |
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