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Placental growth factor (PlGF) enhances breast cancer cell motility by mobilising ERK1/2 phosphorylation and cytoskeletal rearrangement

BACKGROUND: During metastasis, cancer cells migrate away from the primary tumour and invade the circulatory system and distal tissues. The stimulatory effect of growth factors has been implicated in the migration process. Placental growth factor (PlGF), expressed by 30–50% of primary breast cancers,...

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Detalles Bibliográficos
Autores principales: Taylor, A P, Leon, E, Goldenberg, D M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905300/
https://www.ncbi.nlm.nih.gov/pubmed/20551949
http://dx.doi.org/10.1038/sj.bjc.6605746