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Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk

BACKGROUND: Interpreting proteomic and genomic data is a major challenge in predictive ecotoxicology that can be addressed by a systems biology approach. Mathematical modeling provides an organizational platform to consolidate protein dynamics with possible genomic regulation. Here, a model of ovari...

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Detalles Bibliográficos
Autores principales:	Shoemaker, Jason E, Gayen, Kalyan, Garcia-Reyero, Natàlia, Perkins, Edward J, Villeneuve, Daniel L, Liu, Li, Doyle, Francis J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905341/ https://www.ncbi.nlm.nih.gov/pubmed/20579396 http://dx.doi.org/10.1186/1752-0509-4-89

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