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In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer's disease

BACKGROUND: Alzheimer's disease, known to be associated with the gradual loss of memory, is characterized by low concentration of acetylcholine in the hippocampus and cortex part of the brain. Inhibition of acetylcholinesterase has successfully been used as a drug target to treat Alzheimer'...

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Detalles Bibliográficos
Autores principales:	Ul-Haq, Zaheer, Khan, Waqasuddin, Kalsoom, Saima, Ansari, Farzana L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905356/ https://www.ncbi.nlm.nih.gov/pubmed/20550720 http://dx.doi.org/10.1186/1742-4682-7-22

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