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Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length
BACKGROUND: Poor gene transfer efficiency has been a major problem in developing an effective gene therapy for cystic fibrosis (CF) airway disease. Lysophosphatidylcholine (LPC), a natural airway surfactant, can enhance viral gene transfer in animal models. We examined the electrophysiological and p...
Autores principales: | Cmielewski, Patricia, Anson, Don S, Parsons, David W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905357/ https://www.ncbi.nlm.nih.gov/pubmed/20569421 http://dx.doi.org/10.1186/1465-9921-11-84 |
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