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Differential Regulation of the PGC Family of Genes in a Mouse Model of Staphylococcus aureus Sepsis
The PGC family of transcriptional co-activators (PGC-1α [Ppargc1a], PGC-1β [Ppargc1b], and PRC [Pprc]) coordinates the upregulation of mitochondrial biogenesis, and Ppargc1a is known to be activated in response to mitochondrial damage in sepsis. Therefore, we postulated that the PGC family is regula...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905396/ https://www.ncbi.nlm.nih.gov/pubmed/20657826 http://dx.doi.org/10.1371/journal.pone.0011606 |