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Histone H2A and H2B Are Monoubiquitinated at AID-Targeted Loci
BACKGROUND: Somatic hypermutation introduces base substitutions into the rearranged and expressed immunoglobulin (Ig) variable regions to promote immunity. This pathway requires and is initiated by the Activation Induced Deaminase (AID) protein, which deaminates cytidine to produce uracils and UG mi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905439/ https://www.ncbi.nlm.nih.gov/pubmed/20661291 http://dx.doi.org/10.1371/journal.pone.0011641 |