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The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different
A 10 kb O-antigen gene cluster was sequenced from a Salmonella enterica subsp. enterica Dakar O28 reference strain and from two S. Pomona serogroup O28 isolates. The two S. Pomona O antigen gene clusters showed only moderate identity with the S. Dakar O28 gene cluster, suggesting that the O antigen...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905691/ https://www.ncbi.nlm.nih.gov/pubmed/20652070 http://dx.doi.org/10.1155/2010/209291 |
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author | Clark, Clifford G. Grant, Christopher C. R. Trout-Yakel, Keri M. Tabor, Helen Ng, Lai-King Rahn, Kris Franklin, Kristyn Kropinski, Andrew M. |
author_facet | Clark, Clifford G. Grant, Christopher C. R. Trout-Yakel, Keri M. Tabor, Helen Ng, Lai-King Rahn, Kris Franklin, Kristyn Kropinski, Andrew M. |
author_sort | Clark, Clifford G. |
collection | PubMed |
description | A 10 kb O-antigen gene cluster was sequenced from a Salmonella enterica subsp. enterica Dakar O28 reference strain and from two S. Pomona serogroup O28 isolates. The two S. Pomona O antigen gene clusters showed only moderate identity with the S. Dakar O28 gene cluster, suggesting that the O antigen oligosaccharides may contain one or more sugars conferring the O28 epitope but may otherwise be different. These novel findings are absolutely critical for the correct interpretation of molecular serotyping assays targeting genes within the O antigen gene clusters of these Salmonella serotypes and suggest the possibility that the O antigen gene clusters of other Salmonella serovars may also be heterogenous. |
format | Text |
id | pubmed-2905691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-29056912010-07-22 The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different Clark, Clifford G. Grant, Christopher C. R. Trout-Yakel, Keri M. Tabor, Helen Ng, Lai-King Rahn, Kris Franklin, Kristyn Kropinski, Andrew M. Int J Microbiol Research Article A 10 kb O-antigen gene cluster was sequenced from a Salmonella enterica subsp. enterica Dakar O28 reference strain and from two S. Pomona serogroup O28 isolates. The two S. Pomona O antigen gene clusters showed only moderate identity with the S. Dakar O28 gene cluster, suggesting that the O antigen oligosaccharides may contain one or more sugars conferring the O28 epitope but may otherwise be different. These novel findings are absolutely critical for the correct interpretation of molecular serotyping assays targeting genes within the O antigen gene clusters of these Salmonella serotypes and suggest the possibility that the O antigen gene clusters of other Salmonella serovars may also be heterogenous. Hindawi Publishing Corporation 2010 2010-06-28 /pmc/articles/PMC2905691/ /pubmed/20652070 http://dx.doi.org/10.1155/2010/209291 Text en Copyright © 2010 Clifford G. Clark et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Clark, Clifford G. Grant, Christopher C. R. Trout-Yakel, Keri M. Tabor, Helen Ng, Lai-King Rahn, Kris Franklin, Kristyn Kropinski, Andrew M. The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title | The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title_full | The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title_fullStr | The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title_full_unstemmed | The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title_short | The O28 Antigen Gene Clusters of Salmonella enterica subsp. enterica Serovar Dakar and Serovar Pomona Are Different |
title_sort | o28 antigen gene clusters of salmonella enterica subsp. enterica serovar dakar and serovar pomona are different |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905691/ https://www.ncbi.nlm.nih.gov/pubmed/20652070 http://dx.doi.org/10.1155/2010/209291 |
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