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Asn(12) and Asn(278): Critical Residues for In Vitro Biological Activity of Reteplase

Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome. Though methanol induction of the native and the rPA mutants showed similar expression levels (...

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Detalles Bibliográficos
Autores principales:	Mandi, Naganath, Sundaram, Kalyana R., Tandra, Sunil K., Bandyopadhyay, Suman, Padmanabhan, Sriram
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905703/ https://www.ncbi.nlm.nih.gov/pubmed/20672054 http://dx.doi.org/10.1155/2010/172484

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