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Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin Ligase

Human Arkadia is a nuclear protein consisted of 989 amino acid residues, with a characteristic RING domain in its C-terminus. The RING domain harbours the E3 ubiquitin ligase activity needed by Arkadia to ubiquitinate its substrates such as negative regulators of TGF-β signaling. The RING finger dom...

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Detalles Bibliográficos
Autores principales:	Chasapis, Christos T., Loutsidou, Ariadni K., Orkoula, Malvina G., Spyroulias, Georgios A.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905715/ https://www.ncbi.nlm.nih.gov/pubmed/20689703 http://dx.doi.org/10.1155/2010/323152

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