Cargando…

Inhibition of Melanoma Angiogenesis by Telomere Homolog Oligonucleotides

Telomere homolog oligonucleotides (T-oligos) activate an innate telomere-based program that leads to multiple anticancer effects. T-oligos act at telomeres to initiate signaling through the Werner protein and ATM kinase. We wanted to determine if T-oligos have antiangiogenic effects. We found that T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coleman, Christina, Levine, Danielle, Kishore, Raj, Qin, Gangjian, Thorne, Tina, Lambers, Erin, Sasi, Sharath P., Yaar, Mina, Gilchrest, Barbara A., Goukassian, David A.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906154/ https://www.ncbi.nlm.nih.gov/pubmed/20652008 http://dx.doi.org/10.1155/2010/928628

Ejemplares similares

Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment
por: Weng, Desheng, et al.
Publicado: (2010)

Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells
por: Yaar, Mina, et al.
Publicado: (2007)

BREAKING THE “HARMONY” OF TNF-α SIGNALING FOR CANCER TREATMENT
por: Sasi, Sharath P., et al.
Publicado: (2011)

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma
por: Pitman, Ryan T, et al.
Publicado: (2013)

TOPICAL APPLICATION OF THYMIDINE DINUCLEOTIDE TO NEWBORN MICE REDUCES AND DELAYS DEVELOPMENT OF UV-INDUCED MELANOMAS
por: Goukassian, D.A., et al.
Publicado: (2012)

Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes
por: Park, Hee-Young, et al.
Publicado: (2009)

Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants
por: Sasi, Sharath P., et al.
Publicado: (2014)

Correction: Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants
por: Sasi, Sharath P., et al.
Publicado: (2015)

TNF-α and IL-1α but not MCP-1 and Rantes increase significantly the formation of p-H2AX foci in naïve BM-derived TNFR1/p55KO EPCs
por: Sasi, Sharath P., et al.
Publicado: (2014)

Short-Term Treatment with Esmolol Reverses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats via Inhibition of Akt/NF-κB and NFATc4
por: Quintana-Villamandos, Begoña, et al.
Publicado: (2018)

Rosuvastatin Enhances Angiogenesis via eNOS-Dependent Mobilization of Endothelial Progenitor Cells
por: Zhou, Junlan, et al.
Publicado: (2013)

Therapeutic manipulation of angiogenesis with miR-27b
por: Veliceasa, Dorina, et al.
Publicado: (2015)

Oligonucleotides Targeting Telomeres and Telomerase in Cancer
por: Schrank, Zachary, et al.
Publicado: (2018)

Radiation-associated degenerative cardiovascular risks during normal aging and after adverse CV event 10 months post-initial exposure
por: Sasi, Sharath P., et al.
Publicado: (2014)

hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang
por: Mulnix, Richard E, et al.
Publicado: (2013)

IL-10 Accelerates Re-Endothelialization and Inhibits Post-Injury Intimal Hyperplasia following Carotid Artery Denudation
por: Verma, Suresh K., et al.
Publicado: (2016)

Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers
por: Muralidharan, Sujatha, et al.
Publicado: (2015)

Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers
por: Muralidharan, Sujatha, et al.
Publicado: (2015)

Radiation-associated cardiovascular risks for future deep-space missions
por: Yan, Xinhua, et al.
Publicado: (2014)

The many facets of homologous recombination at telomeres
por: Claussin, Clémence, et al.
Publicado: (2015)

Hole Migration in Telomere‐Based Oligonucleotide Anions and G‐Quadruplexes
por: Li, Wen, et al.
Publicado: (2019)

Barbara A. Gilchrest: A world-renowned dermatologist and researcher, a great mentor, an educator, former president of the Society for Investigative Dermatology, editor-in-chief of The Journal of Investigative Dermatology, and a devoted friend
por: Yaar, Mina
Publicado: (2015)

Optimizing the Design of Oligonucleotides for Homology Directed Gene Targeting
por: Miné-Hattab, Judith, et al.
Publicado: (2011)

Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells
por: Sasi, Sharath P., et al.
Publicado: (2015)

Corrigendum to “Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells”
por: Sasi, Sharath P., et al.
Publicado: (2016)

Functional disruption of α4 integrin mobilizes bone marrow–derived endothelial progenitors and augments ischemic neovascularization
por: Qin, Gangjian, et al.
Publicado: (2006)

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA
por: Langerak, Petra, et al.
Publicado: (2005)

Telomeric Repeat-Binding Factor Homologs in Entamoeba histolytica: New Clues for Telomeric Research
por: Rendón-Gandarilla, Francisco Javier, et al.
Publicado: (2018)

Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation
por: Yan, Xinhua, et al.
Publicado: (2014)

Correction: Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation
por: Yan, Xinhua, et al.
Publicado: (2015)

Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia
por: Cimini, Maria, et al.
Publicado: (2021)

Telomeric Trans-Silencing in Drosophila melanogaster: Tissue Specificity, Development and Functional Interactions between Non-Homologous Telomeres
por: Josse, Thibaut, et al.
Publicado: (2008)

Potential role of hydrogen sulfide in diabetes-impaired angiogenesis and ischemic tissue repair
por: Cheng, Zhongjian, et al.
Publicado: (2020)

RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination
por: Uringa, Evert-Jan, et al.
Publicado: (2011)

SIRT1 contributes to telomere maintenance and augments global homologous recombination
por: Palacios, Jose A., et al.
Publicado: (2010)

Transcription of telomeric DNA leads to high levels of homologous recombination and t-loops
por: Kar, Anirban, et al.
Publicado: (2016)

Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells
por: Mao, Pingsu, et al.
Publicado: (2016)

Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons
por: Saint-Leandre, Bastien, et al.
Publicado: (2020)

STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma
por: Klein, Jonah D., et al.
Publicado: (2014)

X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells
por: De Vitis, Marco, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tac7880uivhgqtr3r3108jtg92