Temporal Interleukin-1β Secretion from Primary Human Peripheral Blood Monocytes by P2X7-independent and P2X7-dependent Mechanisms

The processing and regulated secretion of IL-1β are critical points of control of the biological activity of this important pro-inflammatory cytokine. IL-1β is produced by both monocytes and macrophages, but the rate and mechanism of release differ according to the differentiation status and the ori...

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Detalles Bibliográficos
Autores principales: Ward, Jon R., West, Peter W., Ariaans, Mark P., Parker, Lisa C., Francis, Sheila E., Crossman, David C., Sabroe, Ian, Wilson, Heather L.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906308/
https://www.ncbi.nlm.nih.gov/pubmed/20495003
http://dx.doi.org/10.1074/jbc.M109.072793

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