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Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen

Arterial thrombosis, a major cause of myocardial infarction and stroke, is initiated by activation of blood platelets by subendothelial collagen. The protein kinase C (PKC) family centrally regulates platelet activation, and it is becoming clear that the individual PKC isoforms play distinct roles,...

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Detalles Bibliográficos
Autores principales:	Gilio, Karen, Harper, Matthew T., Cosemans, Judith M. E. M., Konopatskaya, Olga, Munnix, Imke C. A., Prinzen, Lenneke, Leitges, Michael, Liu, Qinghang, Molkentin, Jeffery D., Heemskerk, Johan W. M., Poole, Alastair W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906332/ https://www.ncbi.nlm.nih.gov/pubmed/20479008 http://dx.doi.org/10.1074/jbc.M110.136176

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