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Canonical Transient Receptor Potential 6 (TRPC6), a Redox-regulated Cation Channel

This study examined the effect of H(2)O(2) on the TRPC6 channel and its underlying mechanisms using a TRPC6 heterologous expression system. In TRPC6-expressing HEK293T cells, H(2)O(2) significantly stimulated Ca(2+) entry in a dose-dependent manner. Electrophysiological experiments showed that H(2)O...

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Detalles Bibliográficos
Autores principales:	Graham, Sarabeth, Ding, Min, Ding, Yanfeng, Sours-Brothers, Sherry, Luchowski, Rafal, Gryczynski, Zygmunt, Yorio, Thomas, Ma, Haiying, Ma, Rong
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906337/ https://www.ncbi.nlm.nih.gov/pubmed/20501650 http://dx.doi.org/10.1074/jbc.M109.093500

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