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Different conformations of nascent polypeptides during translocation across the ER membrane

BACKGROUND: In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent proteins can fold already within the ribosome-translocon channel, and previous studies suggest that only a limited degree of folding (such...

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Detalles Bibliográficos
Autores principales: Mingarro, Ismael, Nilsson, IngMarie, Whitley, Paul, von Heijne, Gunnar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29064/
https://www.ncbi.nlm.nih.gov/pubmed/11178101
http://dx.doi.org/10.1186/1471-2121-1-3

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