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Different conformations of nascent polypeptides during translocation across the ER membrane
BACKGROUND: In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent proteins can fold already within the ribosome-translocon channel, and previous studies suggest that only a limited degree of folding (such...
Autores principales: | Mingarro, Ismael, Nilsson, IngMarie, Whitley, Paul, von Heijne, Gunnar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29064/ https://www.ncbi.nlm.nih.gov/pubmed/11178101 http://dx.doi.org/10.1186/1471-2121-1-3 |
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