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Saccharomyces cerevisiae-based system for studying clustered DNA damages
DNA-damaging agents can induce clustered lesions or multiply damaged sites (MDSs) on the same or opposing DNA strands. In the latter, attempts to repair MDS can generate closely opposed single-strand break intermediates that may convert non-lethal or mutagenic base damage into double-strand breaks (...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906745/ https://www.ncbi.nlm.nih.gov/pubmed/20552213 http://dx.doi.org/10.1007/s00411-010-0303-3 |