Modifying 5-HT1A Receptor Gene Expression as a New Target for Antidepressant Therapy

Major depression is the most common form of mental illness, and is treated with antidepressant compounds that increase serotonin (5-HT) neurotransmission. Increased 5-HT1A autoreceptor levels in the raphe nuclei act as a “brake” to inhibit the 5-HT system, leading to depression and resistance to ant...

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Detalles Bibliográficos
Autores principales: Albert, Paul R., Le François, Brice
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907233/
https://www.ncbi.nlm.nih.gov/pubmed/20661455
http://dx.doi.org/10.3389/fnins.2010.00035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907233/
https://www.ncbi.nlm.nih.gov/pubmed/20661455
http://dx.doi.org/10.3389/fnins.2010.00035

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