The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

BACKGROUND: Aberrations in the Wnt pathway have been reported to be involved in the metastasis of prostate cancer (PCa) to bone. We investigated the effect and underlying mechanism of a naturally-occurring Wnt inhibitor, WIF1, on the growth and cellular invasiveness of a bone metastatic PCa cell lin...

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Detalles Bibliográficos
Autores principales: Yee, David S, Tang, Yaxiong, Li, Xuesen, Liu, Zhongbo, Guo, Yi, Ghaffar, Samia, McQueen, Peter, Atreya, Dash, Xie, Jun, Simoneau, Anne R, Hoang, Bang H, Zi, Xiaolin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907330/
https://www.ncbi.nlm.nih.gov/pubmed/20573255
http://dx.doi.org/10.1186/1476-4598-9-162

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