Reversible bone pain and symmetric bone scan uptake in a dialysis patient treated with cinacalcet: a case report

INTRODUCTION: The medical management of secondary hyperparathyroidism in patients with end-stage renal disease involves a combination of dietary restrictions, phosphate binders, active vitamin D analogs, and calcimimetics. CASE PRESENTATION: We report the case of a 36-year-old Hispanic dialysis pati...

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Detalles Bibliográficos
Autores principales: Lenz, Oliver, Sancassani, Rhea, Bottino, Carla, Fornoni, Alessia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907400/
https://www.ncbi.nlm.nih.gov/pubmed/20576153
http://dx.doi.org/10.1186/1752-1947-4-191
Descripción
Sumario:INTRODUCTION: The medical management of secondary hyperparathyroidism in patients with end-stage renal disease involves a combination of dietary restrictions, phosphate binders, active vitamin D analogs, and calcimimetics. CASE PRESENTATION: We report the case of a 36-year-old Hispanic dialysis patient, originally from Cuba and now residing in the USA, who developed severe bone pain and muscle twitching after starting low dose cinacalcet, despite normal pre-dialysis ionized calcium and elevated parathyroid hormone. The clinical symptoms correlated with increased symmetrical uptake on bone scan that resolved rapidly upon discontinuation of cinacalcet. CONCLUSION: Cinacalcet may induce severe bone pain and a unique bone scan uptake pattern in hemodialysis patients.

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