Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering

Telomerase is a ribonucleoprotein enzyme that synthesizes telomeric DNA. The reactivation of telomerase activity by aberrant upregulation/expression of its catalytic subunit hTERT is a major pathway in human tumorigenesis. However, regulatory mechanisms that control hTERT expression are largely unkn...

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Detalles Bibliográficos
Autores principales: Abe, Satoshi, Tanaka, Hiromi, Notsu, Tomomi, Horike, Shin-ichi, Fujisaki, Chikako, Qi, Dong-Lai, Ohhira, Takahito, Gilley, David, Oshimura, Mitsuo, Kugoh, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907559/
https://www.ncbi.nlm.nih.gov/pubmed/20678252
http://dx.doi.org/10.1186/2041-9414-1-6

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