Cargando…

Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer

BACKGROUND: Development of innovative, effective therapies against recurrent/chemotherapy-resistant ovarian cancer remains a high priority. Using high-throughput technologies to analyze genetic fingerprints of ovarian cancer, we have discovered extremely high expression of the genes encoding the pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cocco, Emiliano, Casagrande, Francesca, Bellone, Stefania, Richter, Christine E, Bellone, Marta, Todeschini, Paola, Holmberg, Jennie C, Fu, Han Hsuan, Montagna, Michele K, Mor, Gil, Schwartz, Peter E, Arin-Silasi, Dan, Azoudi, Masoud, Rutherford, Thomas J, Abu-Khalaf, Maysa, Pecorelli, Sergio, Santin, Alessandro D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908101/ https://www.ncbi.nlm.nih.gov/pubmed/20598131 http://dx.doi.org/10.1186/1471-2407-10-349

Ejemplares similares

Expression of Tissue factor in Adenocarcinoma and Squamous Cell Carcinoma of the Uterine Cervix: Implications for immunotherapy with hI-con1, a factor VII-IgGF(c )chimeric protein targeting tissue factor
por: Cocco, Emiliano, et al.
Publicado: (2011)

Clostridium Perfringens Enterotoxin (CPE) and CPE-Binding Domain (c-CPE) for the Detection and Treatment of Gynecologic Cancers
por: Black, Jonathan D., et al.
Publicado: (2015)

hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma
por: Cocco, E, et al.
Publicado: (2010)

On the Interaction of Clostridium perfringens Enterotoxin with Claudins
por: Veshnyakova, Anna, et al.
Publicado: (2010)

In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma
por: El-Sahwi, K, et al.
Publicado: (2010)

Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody
por: Raji, Rhoda, et al.
Publicado: (2011)

Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications
por: Freedman, John C., et al.
Publicado: (2016)

Claudins Overexpression in Ovarian Cancer: Potential Targets for Clostridium Perfringens Enterotoxin (CPE) Based Diagnosis and Therapy
por: English, Diana P., et al.
Publicado: (2013)

Molecular Cloning and Functional Characterization of the Receptor for Clostridium perfringens Enterotoxin
por: Katahira, Jun, et al.
Publicado: (1997)

Bystander Host Cell Killing Effects of Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2016)

Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin
por: Ogbu, Chinemerem P., et al.
Publicado: (2023)

Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy
por: Bellone, S, et al.
Publicado: (2012)

A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin
por: Lohrberg, Dörte, et al.
Publicado: (2009)

Humans as Reservoir for Enterotoxin Gene–carrying Clostridium perfringens Type A
por: Heikinheimo, Annamari, et al.
Publicado: (2006)

Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab
por: Todeschini, P, et al.
Publicado: (2011)

Use of Clostridium perfringens Enterotoxin and the Enterotoxin Receptor-Binding Domain (C-CPE) for Cancer Treatment: Opportunities and Challenges
por: Gao, Zhijian, et al.
Publicado: (2012)

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy
por: Pahle, Jessica, et al.
Publicado: (2017)

Targeting claudin‐overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin
por: Piontek, Anna, et al.
Publicado: (2020)

Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2019)

NanI Sialidase Enhances the Action of Clostridium perfringens Enterotoxin in the Presence of Mucus
por: Navarro, Mauricio A., et al.
Publicado: (2021)

Specificity of Interaction between Clostridium perfringens Enterotoxin and Claudin-Family Tight Junction Proteins
por: Mitchell, Leslie A., et al.
Publicado: (2010)

C-Terminal Clostridium perfringens Enterotoxin-Mediated Antigen Delivery for Nasal Pneumococcal Vaccine
por: Suzuki, Hidehiko, et al.
Publicado: (2015)

Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers
por: Benz, Roland, et al.
Publicado: (2018)

Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells
por: Beier, Laura-Sophie, et al.
Publicado: (2019)

Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut
por: Vecchio, Alex J., et al.
Publicado: (2021)

Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes
por: Orlando, Benjamin J., et al.
Publicado: (2022)

Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to In Vivo and In Vitro Permeability Effects
por: Shrestha, Archana, et al.
Publicado: (2022)

Serum amyloid A (SAA): a novel biomarker for uterine serous papillary cancer
por: Cocco, E, et al.
Publicado: (2009)

Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2013)

Effects of Bile Acids and Nisin on the Production of Enterotoxin by Clostridium perfringens in a Nutrient-Rich Medium
por: Park, Miseon, et al.
Publicado: (2018)

Development of Adjuvant-Free Bivalent Food Poisoning Vaccine by Augmenting the Antigenicity of Clostridium perfringens Enterotoxin
por: Suzuki, Hidehiko, et al.
Publicado: (2018)

Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/Polyps with Dysplasia
por: Fujiwara-Tani, Rina, et al.
Publicado: (2020)

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas
por: Nakashima, Chie, et al.
Publicado: (2020)

RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2019)

Innovative and Highly Sensitive Detection of Clostridium perfringens Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies
por: Neumann, Thea, et al.
Publicado: (2021)

Application of C-Terminal Clostridium Perfringens Enterotoxin in Treatment of Brain Metastasis from Breast Cancer
por: Banga, Amita R., et al.
Publicado: (2022)

NanH Is Produced by Sporulating Cultures of Clostridium perfringens Type F Food Poisoning Strains and Enhances the Cytotoxicity of C. perfringens Enterotoxin
por: Li, Jihong, et al.
Publicado: (2021)

T-DM1, a novel antibody–drug conjugate, is highly effective against primary HER2 overexpressing uterine serous carcinoma in vitro and in vivo
por: English, Diana P, et al.
Publicado: (2014)

Identification and Characterization of a New Enterotoxin Produced by Clostridium perfringens Isolated from Food Poisoning Outbreaks
por: Irikura, Daisuke, et al.
Publicado: (2015)

The Potential Therapeutic Agent Mepacrine Protects Caco-2 Cells against Clostridium perfringens Enterotoxin Action
por: Freedman, John C., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qu28ma1to5jpk1u3r6jgv4hkr3