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Synthetic Heparan Sulfate Oligosaccharides Inhibit Endothelial Cell Functions Essential for Angiogenesis

BACKGROUND: Heparan sulfate (HS) is an important regulator of the assembly and activity of various angiogenic signalling complexes. However, the significance of precisely defined HS structures in regulating cytokine-dependent angiogenic cellular functions and signalling through receptors regulating...

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Detalles Bibliográficos
Autores principales: Cole, Claire L., Hansen, Steen U., Baráth, Marek, Rushton, Graham, Gardiner, John M., Avizienyte, Egle, Jayson, Gordon C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908126/
https://www.ncbi.nlm.nih.gov/pubmed/20657775
http://dx.doi.org/10.1371/journal.pone.0011644