R5 Clade C SHIV Strains with Tier 1 or 2 Neutralization Sensitivity: Tools to Dissect Env Evolution and to Develop AIDS Vaccines in Primate Models

BACKGROUND: HIV-1 clade C (HIV-C) predominates worldwide, and anti-HIV-C vaccines are urgently needed. Neutralizing antibody (nAb) responses are considered important but have proved difficult to elicit. Although some current immunogens elicit antibodies that neutralize highly neutralization-sensitiv...

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Detalles Bibliográficos
Autores principales: Siddappa, Nagadenahalli B., Watkins, Jennifer D., Wassermann, Klemens J., Song, Ruijiang, Wang, Wendy, Kramer, Victor G., Lakhashe, Samir, Santosuosso, Michael, Poznansky, Mark C., Novembre, Francis J., Villinger, François, Else, James G., Montefiori, David C., Rasmussen, Robert A., Ruprecht, Ruth M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908149/
https://www.ncbi.nlm.nih.gov/pubmed/20657739
http://dx.doi.org/10.1371/journal.pone.0011689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908149/
https://www.ncbi.nlm.nih.gov/pubmed/20657739
http://dx.doi.org/10.1371/journal.pone.0011689

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