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Variations in Gnai2 and Rgs1 Expression Affect Chemokine Receptor Signaling and the Organization of Secondary Lymphoid Organs
Ligand bound chemoattractant receptors activate the heterotrimeric G protein Gi to stimulate downstream signaling pathways to properly position lymphocytes in lymphoid organs. Here we show how variations the expression of a chemokine receptor and in two components in the signaling pathway, Gα(i2) an...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908210/ https://www.ncbi.nlm.nih.gov/pubmed/20508603 http://dx.doi.org/10.1038/gene.2010.27 |