The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

DNA double-strand breaks (DSBs) can be repaired by homologous recombination (HR), which can involve Holliday junction (HJ) intermediates that are ultimately resolved by nucleolytic enzymes. An N-terminal fragment of human GEN1 has recently been shown to act as a Holliday junction resolvase, but litt...

Descripción completa

Detalles Bibliográficos
Autores principales: Bailly, Aymeric P., Freeman, Alasdair, Hall, Julie, Déclais, Anne-Cécile, Alpi, Arno, Lilley, David M. J., Ahmed, Shawn, Gartner, Anton
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908289/
https://www.ncbi.nlm.nih.gov/pubmed/20661466
http://dx.doi.org/10.1371/journal.pgen.1001025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908289/
https://www.ncbi.nlm.nih.gov/pubmed/20661466
http://dx.doi.org/10.1371/journal.pgen.1001025

Ejemplares similares