Dasatinib impairs long-term expansion of leukemic progenitors in a subset of acute myeloid leukemia cases

A number of signaling pathways might be frequently disrupted in acute myeloid leukemia (AML). We questioned whether the dual SRC/ABL kinase inhibitor dasatinib can affect AML cells and whether differences can be observed with normal CD34(+) cells. First, we demonstrated that normal cord blood (CB) C...

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Detalles Bibliográficos
Autores principales: Han, Lina, Schuringa, Jan Jacob, Mulder, André, Vellenga, Edo
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908401/
https://www.ncbi.nlm.nih.gov/pubmed/20387067
http://dx.doi.org/10.1007/s00277-010-0948-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908401/
https://www.ncbi.nlm.nih.gov/pubmed/20387067
http://dx.doi.org/10.1007/s00277-010-0948-7

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