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Dasatinib impairs long-term expansion of leukemic progenitors in a subset of acute myeloid leukemia cases
A number of signaling pathways might be frequently disrupted in acute myeloid leukemia (AML). We questioned whether the dual SRC/ABL kinase inhibitor dasatinib can affect AML cells and whether differences can be observed with normal CD34(+) cells. First, we demonstrated that normal cord blood (CB) C...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908401/ https://www.ncbi.nlm.nih.gov/pubmed/20387067 http://dx.doi.org/10.1007/s00277-010-0948-7 |